He was the nephew (sister’s son) as well as the son-in-law of Hadhrat Shaikh Jalalud Deen. His father, Shah Abdush Shakْr too was the khalifah of Hadhrat Jalalud Deen. Hadhrat Nizamuddin acquired the mantle of khilaafate from Hadhrat Shaikh Jalaluddin.
He delivered numerous discourses on Uloom-e-Asraar (Knowledge of spiritual mysteries) and Haqaa-iq, (spiritual realities). Most of his statements have been recorded by his khuddaam.
According to some sources he acquired distinction in Uloom-e-Zaahiri without having pursued an academic career. Night and day he engaged in Thikr Nafi-Ithbaat (a form of Thikr) and Thikr bil jahr (audible zik). He engaged in such intensive zikr that he would not emerge from the room for a full month.
He was an expert of Uloom-e-Zaahiriyyah and Baatiniyyah. Besides the knowledge of Ma’rifat and Spiritual Mysteries, he was an expert in chemistry and other branches of knowledge as well. As a result of his fame in all fields of knowledge, envious persons harboured malice for him. They would repeatedly complain about him to the king, Akbar who had Hadhrat twice exiled from Hindustan. The first time he was sent to the Haramain Shareefain. After spending some time there he returned to Hindustan. The second time he was exiled to Central Asia. Here too envious people complained about him to the governor of Balkh who intended to expel Hadhrat Shaikh. But, in a dream Rasulullah (صلى الله عايه وسالم) forbade the governor. In consequence of this dream the governor became and ardent devotee and became Hadhrat’s mureed.
It is a karaamat of Hadhrat that the malaa-ikah in human form would join him in Salaat. He would be the Imaam and they the muqtadis.
Taking 6 months leave from his Shaikh he went to Balkh, saying that he will either attain the goal of his quest or if this has not been destined for him, he will take pardah there. On his departure Hadhrat Shaikh instructed him to make zikr of the Ism-e-Zaat (Allahu) 90 times in a single breath, gradually increasing the number in accordance with his ability. Ultimately, he developed his ability to the extent of up to 400 times with a single breath. Only a month had passed when the manifestation of Tajalliyaat-e-Khaassah (Special Divine Illumination which defines rational understanding and expression) began. Since he had no need for much solitude, Hadhrat Shaikh, discouraged him from it. Hadhrat Shaikh then ordered him to guide and instruct others (in Sulook). It is a well-established fact that during his very lifetime Hadhrat Jalaluddin had referred all his khulafaa and mureedeen to Hadhrat Shaikh Nizamud Deen.
Hadhrat Shaikh Nizamud Deen attended to their ta’leem and talqeen. He attended to the accomplishment (takmeel) of Shaikh Abu Saeed Gangohi who was to be his khalifah and representative in Hindustan. Any person on whom Hadhrat cast his gaze, would become a Saahib-e-Shuhood immediately. (Saahib-e-Shuhood is a high-ranking Wali whose soul dwells in a lofty state of Divine Presence and Perception – Translator)
It was for this reason that he became known as Wali Taraash (Maker of Saints).
Hadhrat Shaikh passed away on the 8th Rajab in the year 1024 or 1035 or 1036 AH. His grave is in Balkh. His senior khulafaa are his son, Shaikh Abdul Kareem and Sayyid Ali Ghawwas who remained in Balkh while Hadhrat Shah Abu Saeed took over the spiritual representation of his Shaikh in Gangohi.